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How ELISA testing can be/is being used for COVID-19 serological antibody testing Assignment | Online Assignment

Covid-19 diagnostic testing, antibody testing, and tracing, are regarded as key to reopening countries currently dealing with the coronavirus pandemic. The assignment is to research current scientific literature and write a paper dealing with why and how ELISA testing can be/is being used for COVID-19 serological antibody testing. Considerations for the paper: – ELISA antibody testing vs. diagnostic antigen testing. – Significance of isotype detection: IgM vs. IgG, and timing – Distinction between presence of antigen-specific antibodies and immunity – Specificity: the SARS-CoV-2 virus that causes Covid-19, as well as SARS, MERS, and the common cold, are all coronaviruses – how would an ELISA test distinguish among exposure to them – Test accuracy: sensitivity vs. specificity -Bayes Theorem as applies to test sensitivity and specificity -How might one arrive at a prior hypothesis? -Random vs. non-random sample testing in evaluating the assay -Effect of the frequency of a disease in the population Follow the format of abstract, introduction, discussion and conclusion

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