Adaptations to high elevation in tibet | Quick Homework Help

Human populations originally descended from Africa. From there, several expansions into new habitats and environments resulted in cultural and genetic adaptation. One of these adaptations involved the low-oxygen habitats that occur at high altitude. Residents of the Tibetan Plateau live above 4000m with oxygen concentrations that are nearly half of that experienced by human populations at sea level. Low oxygen levels can result in oxygen deprivation that hampers physical performance and reduces newborn survival rates.
Tibetans who have long heritage on the plateau possess physiological differences from those who live at sea level. Many of these features involve the ability of their blood cells to use oxygen more efficiently at such low air pressure. It’s been hypothesized that these features are unique adaptations to their challenging habitat.
Yi et al. 2010 investigated the entire genome of Tibetan populations. They sampled 50 unrelated individuals and identified several genes that are involved in avoiding “hypoxia” (widespread deprivation of oxygen). Then, they compared the DNA sequences in Tibetan individuals to 40 individuals from China and 200 individuals from Denmark (Fig. 2). Based on these comparisons, they identified Tibet-specific alleles for the EPASItranscription factor gene, several genes associated with making different forms of hemoglobin and a gene,DISC1, associated with schizophrenia induced by low oxygen during pregnancy.

To look for evidence of adaptation in Tibetan populations at the EPASI locus, they looked at an aIDitional 366 individuals from different regions in Tibet. They hypothesized that individuals that had two copies of the Tibet-specific allele (E’) would be more common than any other genotype since the gene is involved in avoiding hypoxia. Indeed, they found that the E’ allele (Tibet-specific), was at higher frequency in Tibet than either China or Denmark. They also found that the E’E’ genotype was much more common in Tibetan populations.

If a single nucleotide is important in coping with hypoxia, in which codon position might you expect to find nucleotide differences? Why?

Don't use plagiarized sources. Get Your Custom Essay on
Adaptations to high elevation in tibet | Quick Homework Help
Get an essay WRITTEN FOR YOU, Plagiarism free, and by an EXPERT!
Order Essay

I just do not understand because I thought the 3rd codon position was best to not mess up the genetic code but then natural selection to pass down heritably is better in position 1 or 2 codon.

Quick Homework Essays
Calculate your paper price
Pages (550 words)
Approximate price: -

Why Work with Us

Top Quality and Well-Researched Papers

We always make sure that writers follow all your instructions precisely. You can choose your academic level: high school, college/university or professional, and we will assign a writer who has a respective degree.

Professional and Experienced Academic Writers

We have a team of professional writers with experience in academic and business writing. Many are native speakers and able to perform any task for which you need help.

Free Unlimited Revisions

If you think we missed something, send your order for a free revision. You have 10 days to submit the order for review after you have received the final document. You can do this yourself after logging into your personal account or by contacting our support.

Prompt Delivery and 100% Money-Back-Guarantee

All papers are always delivered on time. In case we need more time to master your paper, we may contact you regarding the deadline extension. In case you cannot provide us with more time, a 100% refund is guaranteed.

Original & Confidential

We use several writing tools checks to ensure that all documents you receive are free from plagiarism. Our editors carefully review all quotations in the text. We also promise maximum confidentiality in all of our services.

24/7 Customer Support

Our support agents are available 24 hours a day 7 days a week and committed to providing you with the best customer experience. Get in touch whenever you need any assistance.

Try it now!

Calculate the price of your order

Total price:

How it works?

Follow these simple steps to get your paper done

Place your order

Fill in the order form and provide all details of your assignment.

Proceed with the payment

Choose the payment system that suits you most.

Receive the final file

Once your paper is ready, we will email it to you.

Our Services

No need to work on your paper at night. Sleep tight, we will cover your back. We offer all kinds of writing services.


Essay Writing Service

No matter what kind of academic paper you need and how urgent you need it, you are welcome to choose your academic level and the type of your paper at an affordable price. We take care of all your paper needs and give a 24/7 customer care support system.


Admission Essays & Business Writing Help

An admission essay is an essay or other written statement by a candidate, often a potential student enrolling in a college, university, or graduate school. You can be rest assurred that through our service we will write the best admission essay for you.


Editing Support

Our academic writers and editors make the necessary changes to your paper so that it is polished. We also format your document by correctly quoting the sources and creating reference lists in the formats APA, Harvard, MLA, Chicago / Turabian.


Revision Support

If you think your paper could be improved, you can request a review. In this case, your paper will be checked by the writer or assigned to an editor. You can use this option as many times as you see fit. This is free because we want you to be completely satisfied with the service offered.